The Linington lab is focused upon contemporary applications of marine natural products chemistry to biological problems. We are interested in developing new methodologies in the areas of marine microbiology, chemical probe design and neglected infectious disease drug discovery. The research in this lab lies at the interface between chemistry and biology and aims to apply the traditional techniques of natural products drug discovery to novel target systems with the dual aims of identifying lead compounds for orphan diseases and furthering our understanding of basic biological processes in these organisms. Our growing library of unique natural products extracts provides a rich resource for the discovery of novel chemotypes with potent and selective biological profiles.