Biomedical Science

The Biomedical Research Initiative aims to advance our molecular understanding of human disease, as well as to develop novel diagnostic and therapeutic tools.

Biochemistry/Biophysics

Einarsdóttir, Professor of Chemistry and Biochemistry
Time-resolved spectroscopy, biophysics and bioenergetics, ligand binding and electron transfer dynamics of redox metalloproteins, heme-copper oxidases, proton translocation

Holman, Professor of Chemistry and Biochemistry
Biological chemistry, bioinorganic chemistry, enzymology, inhibitor design and drug discovery

Kliger, Distinguished Research Professor of Chemistry and Biochemistry, Emeritus
Time-resolved laser spectroscopy, biophysics, studies of visual transduction, protein function, and protein folding

McKinnie, Assistant Professor of Chemistry and Biochemistry
Organic Chemistry; Chemical Biology; Biochemistry; Chemistry; DNA, RNA, Proteins

Millhauser, Distinguished Professor of Chemistry and Biochemistry
Electron spin resonance; nuclear magnetic resonance, melanocortin receptor signaling, agouti and agouti-related proteins, prions, solid phase protein sy

Partch, Associate Professor of Chemistry and Biochemistry
Biochemistry and biophysics, nuclear magnetic resonance spectroscopy; molecular mechanism of circadian rhythmicity

Rubin,  Professor of Chemistry and Biochemistry
Biochemistry and structural biology; molecular mechanisms of cell-cycle regulation, x-ray crystallography, electron microscopy, nuclear magnetic resonance

Scott, Professor of Chemistry and Biochemistry, Faculty Undergraduate Advisor
Three-dimensional atomic structure and function of ribozymes, enzymes, and RNA-protein complexes, static and time-resolved X-ray crystallography, development of structure-based anti-viral agents, RNA evolution,origin of catalysis, and the origin of life.

Sgourakis, Assistant Professor of Chemistry and Biochemistry
Molecular & Structural Immunology; T cell receptor signaling dynamics; MHC-I peptide loading mechanism; Tumor neoantigen characterization (in collaboration with David Haussler’s BME group); Modeling protein complexes from sparse NMR data.

Stone, Associate Professor of Chemistry and Biochemistry, Graduate Program Director
Molecular Mechanisms of Telomerase and Telomeres, Single Molecule Biophysical Techniques, Protein-Nucleic Acid Structure and Function, RNA Structure and Dynamics.


Inorganic/Bioinorganic

Johnstone, Assistant Professor of Chemistry and Biochemistry
Medicinal bioinorganic chemistry; synthetic inorganic chemistry; nanoparticle drug delivery; inorganic spectroscopy; small-molecule X-ray crystallography; mammalian and microbiological cell culture, infectious diseases

*Mascharak, Distinguished Professor of Chemistry and Biochemistry
Bioinorganic chemistry, design of antitumor drugs, modeling of active sites of metalloenzymes, design of catalysts for hydrocarbon oxidation, studies on intermediates in non-heme oxygenase chemistry, design of NO-donors for photodynamic therapy


Organic

Crews, Distinguished Research Professor of Chemistry and Biochemistry, Emeritus
Marine natural products chemistry, bioorganic chemistry, organic structural analysis by NMR, natural products of marine macro- and microorganisms

 Lokey, Professor of Chemistry and Biochemistry
Organic chemistry; combinatorial synthesis, biotechnology, molecular cell biology

MacMillan, Professor of Chemistry and Biochemistry
Natural products chemistry, chemical biology, structural elucidation, cancer biology, microbial natural

McKinnie, Assistant Professor of Chemistry and Biochemistry
Organic Chemistry; Chemical Biology; Biochemistry; Chemistry; DNA, RNA, Proteins

Raskatov, Assistant Professor of Chemistry and Biochemistry
Organic synthesis, NMR, molecular modeling, biophysical characterization, molecular biology assaysproducts

Singaram, Professor of Chemistry and Biochemistry
Organic synthesis, organoborane chemistry, heterocyclic chemistry, organometallic chemistry, asymmetric synthesis, biosensors, and natural products chemistry


Physical

Kliger, Distinguished Research Professor of Chemistry and Biochemistry, Emeritus
Time-resolved laser spectroscopy, biophysics, studies of visual transduction, protein function, and protein folding


(* Notates lab currently not accepting grad students)